PZ0377

PF-05236216 hydrochloride

≥98% (HPLC)

• 동의어(들): 4-[3-(4-Fluorophenyl)-1-methyl-1H-pyrazol-4-yl]-6,7-dihydro-6-methyl-5H-pyrrolo[3,4-b]pyridin-5-one hydrochloride, PF-5236216 hydrochloride
• 실험식(Hill 표기법): C₁₈H₁₅FN₄O · HCl
• CAS Number: 1383376-93-9
• Molecular Weight: 358.80
• UNSPSC 코드: 51111800
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• 양식: powder
• 저장 조건: desiccated
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: CN1C=C(C2=CC=NC(CN3C)=C2C3=O)C(C4=CC=C(F)C=C4)=N1.Cl
• InChI: 1S/C18H15FN4O.ClH/c1-22-10-15-16(18(22)24)13(7-8-20-15)14-9-23(2)21-17(14)11-3-5-12(19)6-4-11;/h3-9H,10H2,1-2H3;1H
• InChI key: CLDJMFXSCFWXDI-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

PF-05236216 is a brain penetrant, potent and selective inhibitor of casein kinase 1 delta/epsilon (CK1δ/ε) that modulates circadian rhythms in mice.

brain penetrant, potent and selective inhibitor of casein kinase 1 delta/epsilon (CK1δ/ε)

법적 정보

Sold for research purposes under agreement from Pfizer Inc.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable