R2033

RK-682

≥98% (HPLC)

• 동의어(들): (R)-3-Hexadecanoyl-5-hydroxymethyltetronic acid, (R)-4-Hydroxy-5-(hydroxymethyl)-3-(1-oxohexadecyl)-2(5H)-furanone
• 실험식(Hill 표기법): C₂₁H₃₆O₅
• CAS Number: 150627-37-5
• Molecular Weight: 368.51
• MDL number: MFCD20488046
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329824012
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to tan
• solubility: DMSO, heptane and xylene: ≥8 mg/mL
• 저장 온도: −20°C
• SMILES string: CCCCCCCCCCCCCCCC(=O)C1=C(O)[C@@H](CO)OC1=O
• InChI: 1S/C21H36O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17(23)19-20(24)18(16-22)26-21(19)25/h18,22,24H,2-16H2,1H3/t18-/m1/s1
• InChI key: KZTSLHQKWLYYAC-GOSISDBHSA-N

설명

애플리케이션

RK-682 has been used:

• as a positive control in high-performance liquid chromatography (HPLC)
• as a reference compound in high-performance liqiud chromatography (HPLC)
• as a pan-protein tyrosine phosphatase non-receptor type (PTPN) inhibitor to study its effects on the activated lymphocytes

생화학적/생리학적 작용

RK-682 is a specific and noncompetitive inhibitor of protein tyrosine phosphatase; It inhibited dephosphorylation activity of CD45 and VHR with IC50 54 and 2.0 microM and 4.5 microM against PTP1B.

Specific and noncompetitive inhibitor of protein tyrosine phosphatase.

특징 및 장점

This compound is featured on the Phosphoprotein Phosphatases (Tyrosine) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable