R4408
Chloramphenicol
Ready Made Solution, 100 mg/mL in ethanol: isopropanol (95:5), ≥98% (HPLC)
동의어(들):
D-(-)-threo-2,2-Dichloro-N-[β-hydroxy-α−(hydroxymethyl)-β-(4-nitrophenyl)ethyl]acetamide, D-(-)-threo-2-Dichloroacetamido-1-(4-nitrophenyl)-1,3-propanediol, D-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-4-nitrophenethyl]acetamide
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모든 사진(1)
About This Item
UNSPSC 코드:
51102831
NACRES:
NA.85
추천 제품
Quality Level
분석
≥98% (HPLC)
양식
solution
농도
100 mg/mL in ethanol: isopropanol (95:5)
항생제 활성 스펙트럼
Gram-negative bacteria
Gram-positive bacteria
동작 모드
protein synthesis | interferes
배송 상태
dry ice
저장 온도
−20°C
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애플리케이션
Chloramphenicol is a synthetic antibiotic, isolated from strains of Streptomyces venezuelae. It is often used for bacterial selection in molecular biology applications at 10-20 μg/mL and as a selection agent for transformed cells containing chloramphenicol reistance genes.
생화학적/생리학적 작용
Mode of Action: Chloramphenicol inhibits bacterial protein synthesis by blocking the peptidyl transferase step by binding to the 50S ribosomal subunit and preventing attachment of aminoacyl tRNA to the ribosome. It also inhibits mitochondrial and chloroplast protein synthesis and ribosomal formation of (p)ppGpp, de-pressing rRNA transcription.
Mode of Resistance: Use of chloramphenicol acetyltransferase will acetylate the product and inactivate it.
Antimicrobial Spectrum: This is a broad spectrum antibiotic against gram-positive and gram-negative bacteria, and is used mainly for ophthalmic and veterinary purposes.
Mode of Resistance: Use of chloramphenicol acetyltransferase will acetylate the product and inactivate it.
Antimicrobial Spectrum: This is a broad spectrum antibiotic against gram-positive and gram-negative bacteria, and is used mainly for ophthalmic and veterinary purposes.
포장
10ml
제조 메모
This product is a ready made solution of 100 mg/mL in ethanol:isopropanol (95:5). It is shipped in dry ice and stored at -20°C.
기타 정보
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.Storage class (TRGS 510): Flammable liquids")
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 2
Storage Class Code
3 - Flammable liquids
WGK
WGK 3
Flash Point (°F)
57.2 °F - closed cup
Flash Point (°C)
14.0 °C - closed cup
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