S0191

Sonic Hedgehog Peptide from mouse

≥97% (SDS-PAGE), recombinant, expressed in E. coli, Fused to a histidine tag at the C-terminus, lyophilized powder

• 동의어(들): Shh
• MDL number: MFCD03792594
• UNSPSC 코드: 12352202
• NACRES: NA.32

속성

• 생물학적 소스: mouse
• Quality Level: 200
• 재조합: expressed in E. coli
• 분석: ≥97% (SDS-PAGE)
• 양식: lyophilized powder
• 효능: 0.4-3.0 μg/mL ED₅₀
• 분자량: predicted mol wt 20 kDa
• 포장: pkg of 25 μg
• 저장 조건: avoid repeated freeze/thaw cycles
• 불순물: <1 EU/μg
• UniProt 수납 번호: Q62226
• 저장 온도: −20°C
• 유전자 정보: mouse ... Shh(20423)

설명

일반 설명

Sonic hedgehog (Shh) is a morphogenic glycoprotein. The gene encoding it is localized on mouse chromosome 5.

애플리케이션

Sonic hedgehog peptide from mouse has been used for neural differentiation.

생화학적/생리학적 작용

Cell signaling peptide involved in embryonic morphogenic development of several tissues including Hensen′s node, the notochord, and the neural tube.

Involved in embryonic morphogenic development of several tissues including Hensen′s node, the notochord, and the neural tube.

Sonic hedgehog (Shh) has a role in fracture healing and regeneration. The protein associates with its receptor Patched (Ptc-1), de-represses Smoothened (Smo) and activates the Gli family of transcription factors. Mutations in the Shh pathway have been linked to developmental diseases and cancer.

기타 정보

N-terminal peptide encoding amino acid residues 25-198.

물리적 형태

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline, pH 7.4, containing 5% trehalose and 50 μg of bovine serum albumin per 1 μg of cytokine.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable