S3322

Supercinnamaldehyde

≥98% (HPLC)

• 동의어(들): 1,3-Dihydro-1-methyl-3-(2-oxopropylidene)-2H-Indol-2-one
• 실험식(Hill 표기법): C₁₂H₁₁NO₂
• CAS Number: 70351-51-8
• Molecular Weight: 201.22
• MDL number: MFCD08530327
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329824530
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: faintly red to very dark red
• solubility: DMSO: 10 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: CN1C(=O)C(=C\C(C)=O)\c2ccccc12
• InChI: 1S/C12H11NO2/c1-8(14)7-10-9-5-3-4-6-11(9)13(2)12(10)15/h3-7H,1-2H3/b10-7+
• InChI key: CZKBLHCEDVWPRN-JXMROGBWSA-N

설명

애플리케이션

Supercinnamaldehyde may be used in transient receptor potential ankyrin 1 (TRPA 1)-mediated cell signaling studies.

생화학적/생리학적 작용

Supercinnamaldehyde is a transient receptor potential ankyrin 1 (TRPA1) activator. EC₅₀ = 0.8 μM.

Supercinnamaldehyde is a transient receptor potential ankyrin 1 (TRPA1) activator; EC₅₀ = 0.8 μM; derivative of cinnamaldehyde; covalently binds to and activates TRPA1 receptor (expressed in nociceptive neurons) by modifying its cysteine residues. Covalent modification of reactive cysteines within TRPA1 can cause channel activation, rapidly signaling potential tissue damage through the pain pathway.

주의사항

Air-sensitive

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves