S3523

Surfactin

from Bacillus subtilis, ≥98.0% (HPLC)

• 동의어(들): surfactin C
• 실험식(Hill 표기법): C₅₃H₉₃N₇O₁₃
• CAS Number: 24730-31-2
• Molecular Weight: 1036.34
• UNSPSC 코드: 51102829
• PubChem Substance ID: 24899562
• NACRES: NA.85

속성

• 생물학적 소스: Bacillus subtilis
• Quality Level: 200
• 설명: zwitterionic
• 분석: ≥98.0% (HPLC)
• 양식: powder
• 저장 조건: (Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)
• 색상: white to faint yellow
• CMC: 7.5-20 μmol/L (depending on methods)
• solubility: ethanol: soluble 10 mg/mL
• 항생제 활성 스펙트럼: Gram-negative bacteria; Gram-positive bacteria; fungi; mycoplasma; neoplastics; viruses
• 동작 모드: cell membrane | interferes
• 저장 온도: 2-8°C
• SMILES string: CC(C)CCCCCCCCC[C@@H]1CC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O1
• InChI: 1S/C53H93N7O13/c1-30(2)20-18-16-14-13-15-17-19-21-36-28-43(61)54-37(22-23-44(62)63)47(66)55-38(24-31(3)4)48(67)57-40(26-33(7)8)51(70)60-46(35(11)12)52(71)58-41(29-45(64)65)50(69)56-39(25-32(5)6)49(68)59-42(27-34(9)10)53(72)73-36/h30-42,46H,13-29H2,1-12H3,(H,54,61)(H,55,66)(H,56,69)(H,57,67)(H,58,71)(H,59,68)(H,60,70)(H,62,63)(H,64,65)/t36-,37+,38+,39-,40-,41+,42+,46+/m1/s1
• InChI key: NJGWOFRZMQRKHT-WGVNQGGSSA-N

설명

일반 설명

Chemical structure: peptide

애플리케이션

Surfactin is used as a surfactant to mediate flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. It is also used to study antitumor activity, activity against enveloped viruses, activity against the protoplast of Bacillus megaterium and the activity against Mycoplasma.

생화학적/생리학적 작용

Surfactin is a lipopeptide antibiotic that is composed of one β-hydroxy fatty acid, which has a long fatty acid moiety, and seven amino acids. Three of them have D configurations. It is a powerful biosurfactant that causes lysis of erythrocytes and bacteria. It is also a clotting inhibitor. Surfactin is thought to disrupt or disintegrate membranes via physicochemical interaction with the membranes.

기타 정보

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)