S6256

Sulfamethazine

99.0-101.0% (on dried basis)

• 동의어(들): 4,6-Dimethylsulfadiazine, 4-Amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide, Sulfadimethyldiazine, Sulfadimidine
• 실험식(Hill 표기법): C₁₂H₁₄N₄O₂S
• CAS Number: 57-68-1
• Molecular Weight: 278.33
• Beilstein: 261304
• EC Number: 200-346-4
• MDL number: MFCD00006066
• UNSPSC 코드: 51284910
• PubChem Substance ID: 24899686
• NACRES: NA.85

속성

• Quality Level: 200
• 분석: 99.0-101.0% (on dried basis)
• 양식: powder or crystals
• 저장 조건: (Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)
• 색상: white to off-white
• 항생제 활성 스펙트럼: Gram-negative bacteria; Gram-positive bacteria
• 동작 모드: DNA synthesis | interferes; enzyme | inhibits
• 저장 온도: 2-8°C
• SMILES string: Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
• InChI: 1S/C12H14N4O2S/c1-8-7-9(2)15-12(14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16)
• InChI key: ASWVTGNCAZCNNR-UHFFFAOYSA-N

설명

일반 설명

Chemical structure: sulfonamide

애플리케이션

Sulfamethazine is an antibiotic used to treat bronchitis, prostatitis and urinary tract infections. It is used in disposition and depletion kinetic studies. It is used to develop detection techniques for quantification in fluids such as cows′ milk, honey and swine urine.

생화학적/생리학적 작용

An antimicrobial sulfur drug. Induces CYP3A4 expression and acetylated by N-acetyltransferase. Exhibits sex dependent pharmacokinetics, metabolized by the male specific isoform CYP2C11.

Sulfamethazine is an antimicrobial sulfur drug that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfamethazine is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It induces CYP3A4 expression and is acetylated by N-acetyltransferase. It exhibits sex dependent pharmacokinetics, metabolized by the male specific isoform CYP2C11. Sulfamethazine is bacteriostatic.

포장

25G,100G

기타 정보

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)