S8195

Swainsonine

from Metarrhizium anisopliae, ≥98% (TLC)

• 동의어(들): (1S,2R,8R,8aR)-1,2,8-Octahydroindolizidinetriol
• 실험식(Hill 표기법): C₈H₁₅NO₃
• CAS Number: 72741-87-8
• Molecular Weight: 173.21
• Beilstein: 4175740
• MDL number: MFCD00017554
• UNSPSC 코드: 51102829
• PubChem Substance ID: 24899779
• NACRES: NA.85

속성

• 생물학적 소스: Metarrhizium anisopliae
• Quality Level: 200
• 분석: ≥98% (TLC)
• 양식: lyophilized powder
• 저장 조건: (Keep container tightly closed in a dry and well-ventilated place.)
• 색상: white to faint yellow
• solubility: H₂O: soluble 1 mg/mL
• 항생제 활성 스펙트럼: neoplastics
• 동작 모드: enzyme | inhibits
• 저장 온도: 2-8°C
• SMILES string: O[C@@H]1CCCN2C[C@@H](O)[C@@H](O)C12
• InChI: 1S/C8H15NO3/c10-5-2-1-3-9-4-6(11)8(12)7(5)9/h5-8,10-12H,1-4H2/t5-,6-,7?,8-/m1/s1
• InChI key: FXUAIOOAOAVCGD-DCDLSZRSSA-N

설명

애플리케이션

Swainsonine is a potent inhibitor of various α-mannosidases, especially of α-mannosidase II. It inhibits glycoprotein processing and also acts as immune modulator.

Swainsonine is an indolizidine alkaloid from the plant Metarrhizium anisopliae that is used as a potent α-mannosidase inhibitor. Product S8195 has been used in chemical inhibition assays of CHO Lec2 cells to inhibit glycosylation .

생화학적/생리학적 작용

Swainsonine is a potent α-mannosidase inhibitor. It also has antimetastatic, antiproliferative, and immunomodulatory activity . It also inhibits glycoprotein processing.

포장

1MG

제조 메모

Soluble in water, methanol, DMSO

기타 정보

Keep container tightly closed in a dry and well-ventilated place.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves