SAB3500395

Anti-PDL-2 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 동의어(들): PDL2 Antibody - Anti-PDL-2 antibody produced in rabbit, Pdl2 Antibody, Anti-B7DC, Anti-PD-L2, Anti-Programmed cell death 1 ligand-2, Anti-Programmed death ligand 1
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 분자량: predicted mol wt 30 kDa
• 종 반응성: human, rat, mouse
• 기술: immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• NCBI 수납 번호: NP_079515
• UniProt 수납 번호: Q9BQ51
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... PDCD1LG2(80380)

설명

일반 설명

Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as butyrophilin B7-DC or CD273. It belongs to the immunoglobulin superfamily. The gene encoding PDL-2 is localized on human chromosome 9p24.1.

면역원

PDL-2 antibody was raised against a 16 amino acid peptide from near the center of human PDL-2.

애플리케이션

Anti-PDL-2 antibody produced in rabbit has been used in immunohistochemistry.

생화학적/생리학적 작용

The expression of programmed cell death 1 ligand 2 (PD-L2) or CD antigen 273 (CD273) is up-regulated by interferon-γ (IFNG/IFN-γ) stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with colony-stimulating factor-2 (CSF2) and interleukin-4 (IL-4). PD-L2 is involved in the co-stimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

결합

The action of this antibody can be blocked using blocking peptide SBP3500395.

물리적 형태

Supplied in PBS with 0.02% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable