SAB4200759

Anti-Human IgG3 antibody, Mouse monoclonal

clone HP-6050, purified from hybridoma cell culture

• 동의어(들): Anti-Immunoglobulin G3
• UNSPSC 코드: 12352203
• NACRES: NA.43

속성

• 생물학적 소스: mouse
• Quality Level: 200
• 항체 형태: purified from hybridoma cell culture
• 항체 생산 유형: primary antibodies
• 클론: HP-6050, monoclonal
• 양식: buffered aqueous solution
• 종 반응성: human
• 농도: ~1.0 mg/mL
• 기술: immunoprecipitation (IP): 1-2.5 μg/test using Human IgG3 myeloma; indirect ELISA: 0.15-0.3 μg/mL using 1 μg/ml Human IgG3 myeloma for coating
• 동형: IgG1
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified

설명

일반 설명

Human IgG consist of four subclasses (1-4) that can be recognized by antigenic differences in their heavy chains. They constitute approximately 65, 30, 5 and 4% of the total IgG, respectively. The abundance of the different IgG subclasses in the bloodstream varies with age, IgG1 and IgG3 reach normal adult levels by 5-7 years of age while IgG2 and IgG4 levels rise more slowly, reaching adult levels at about 10 years of age.

면역원

Human IgG3 myeloma proteins covalently coupled to polyaminostyrene (PAS) microbeads

애플리케이션

Anti-Human IgG3 antibody, mouse monoclonal has been used in indirect ELISA and immunoprecipitation.

생화학적/생리학적 작용

IgG1 and IgG3 are the only subclasses capable of adherence to mononuclear phagocytes and are recognized readily by the Fc receptors on various reticulo-endothelial . IgG3 deficiency has been associated with a history of recurrent infectious, leading to chronic lung disease.

물리적 형태

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable