SAB4300592

Anti-PXN (Ab-88) antibody produced in rabbit

affinity isolated antibody

• 동의어(들): Anti-FLJ16691 antibody produced in rabbit, Anti-paxillin antibody produced in rabbit
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 분자량: ~68 kDa
• 종 반응성: human
• 농도: 1 mg/mL
• 기술: indirect immunofluorescence: 1:50-1:100; western blot: 1:500-1:1000
• 동형: IgG
• 면역원 서열: (P-V-Y-G-S)
• NCBI 수납 번호: NP_001074324.1
• UniProt 수납 번호: P49023
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... PXN(5829)

설명

일반 설명

PXN (paxillin) is a focal adhesion-associated tyrosine-based protein, that is present in the cytoplasm. It is a 68kDa protein that is located on chromosome 12q24.

면역원

Peptide sequence around aa. 86-90 (P-V-Y-G-S), according to the protein PXN.

애플리케이션

Anti-PXN (Ab-88) antibody has been used in immunofluorescence.

생화학적/생리학적 작용

Paxillin (PXN) controls signal transduction, cell morphology and motility, cytoskeletal rearrangements, proliferation and apoptosis. It serves as an oncogene, hence it plays a major role in the growth of human carcinomas.

특징 및 장점

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표적 설명

Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).

물리적 형태

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable