SAB4504134

Anti-phospho-CD4 (pSer⁴³³) antibody produced in rabbit

affinity isolated antibody

• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 분자량: antigen 51 kDa
• 종 반응성: mouse, human, rat
• 농도: ~1 mg/mL
• 기술: ELISA: 1:40000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100
• NCBI 수납 번호: P01730
• UniProt 수납 번호: P01730
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: phosphorylation (pSer433)
• 유전자 정보: human ... CD4(920)

설명

일반 설명

CD4 (CD4 molecule) is present in the surface of specific leukocytes. CD4 contains four ecto-domains (D1-D4) of which D1, D2, and D4 contain disulfide bonds. It is mapped to human chromosome 12p13.31. CD4 belongs to the immunoglobulin superfamily (IgSF). It has four extracellular Ig-like domains, a hydrophobic transmembrane region and a 40-residue cytoplasmic tail.

면역원

The antiserum was produced against synthesized peptide derived from human CD4 around the phosphorylation site of Ser433.

Immunogen Range: 401-450

생화학적/생리학적 작용

CD4 (CD4 molecule) helps in the activation of immunostimulatory T-cells. It serves as a primary receptor for HIV-1 entry. Individuals with infectious and chronic inflammatory diseases shows higher level of soluble CD4 (sCD4).

특징 및 장점

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물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable