SAB5200104

Anti-SLC12A3 antibody produced in rabbit

1 mg/mL, affinity isolated antibody

• 동의어(들): Anti-NCC, Anti-Slc12a3
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous glycerol solution
• 분자량: antigen predicted mol wt 160 kDa
• 종 반응성: human, rat, mouse
• 농도: 1 mg/mL
• 기술: western blot: suitable
• NCBI 수납 번호: NP_000330; NP_062218
• UniProt 수납 번호: P55017
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... SLC12A3(6559) ; rat ... Slc12a3(54300)

설명

일반 설명

Solute carrier family 12 member 3 (SLC12A3) is also known as thiazide-sensitive Na⁺-Cl^- cotransporter (NCCT). It is expressed in the apical cells of the distal convoluted tubule. The gene encoding this 1021 amino acid protein is localized on human chromosome 16q13. The gene ID for the protein is 6559.

특이성

Detects ~160 kDa.

면역원

AA74-95 (rat), 76-97 (hum)

생화학적/생리학적 작용

Solute carrier family 12 member 3 (SLC12A3) is one of the major components of the sodium chloride reabsorption pathway. It controls the Cl^- concentration and is also involved in the transepithelial ion absorption and secretion. Mutations in the gene encoding SLC12A3 have been associated with Gitelman syndrome.

This Na-Cl cotransporter is associated with maintaining blood pressure.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

PBS, 50% glycerol, and 0.09% sodium azide

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable