SCP0004

γ Secretase Inhibitor

≥95% (HPLC)

• 실험식(Hill 표기법): C₂₆H₄₁N₃O₅
• Molecular Weight: 475.62
• UNSPSC 코드: 12352200
• NACRES: NA.32

속성

• 분석: ≥95% (HPLC)
• 양식: lyophilized
• 구성: Peptide Content, ≥85%
• 저장 조건: protect from light
• 저장 온도: −20°C

설명

Amino Acid Sequence

Z-Leu-Leu-Nle-al

일반 설명

Gamma-secretase is a protein complex containing presenilin, nicastrin, APH-1, and PEN-2. The leupeptin analogue Z-Leu-Leu-Nle-al (N-benzyloxycarbonyl-Leu-Leu-norleucinal; Benzyloxicarbonyl-Leu-Leu-Nle-CHO (LLNle)) and closely related peptides are used as protease and a gamma secretase inhibitors.

애플리케이션

γ Secretase Inhibitor has been used to study the suppressive miR-129 functions through inhibition on estrogen receptor 1 (ESR1) and NOTCH signaling in breast cancer stem cells.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable