SML0007

Cevimeline hydrochloride hemihydrate

≥95% (HPLC, NMR)

• 동의어(들): AF-102B, SNI-2011
• 실험식(Hill 표기법): C₁₀H₁₇NOS · xHCl · yH₂O
• CAS Number: 153504-70-2
• Molecular Weight: 199.31 (anhydrous free base basis)
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825084
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥95% (HPLC, NMR)
• 양식: powder
• 저장 조건: desiccated
• 색상: white to tan
• solubility: H₂O: ≥25 mg/mL
• 주관자: Daiichi-Sankyo
• 배송 상태: wet ice
• 저장 온도: −20°C
• SMILES string: O.Cl.Cl.C[C@@H]1O[C@@]2(CS1)CN3CC[C@H]2CC3.C[C@@H]4O[C@@]5(CS4)CN6CC[C@H]5CC6
• InChI: 1S/2C10H17NOS.2ClH.H2O/c2*1-8-12-10(7-13-8)6-11-4-2-9(10)3-5-11;;;/h2*8-9H,2-7H2,1H3;2*1H;1H2/t2*8-,10-;;;/m11.../s1
• InChI key: ZSTLCHCDLIUXJE-GMLJRNIPSA-N

설명

애플리케이션

Cevimeline hydrochloride hemihydrate may be used in cell signaling studies.

생화학적/생리학적 작용

Cevimeline is a muscarinic M1 and M3 receptor agonist.

Cevimeline is a muscarinic M1 and M3 receptor agonist. Cevimeline stimulates secretion by the salivary glands and is used to treat the symptoms of dry mouth.

Cevimeline stimulates the peripheral muscarinic acetylcholine receptors of salivary glands and increases the concentration of Ca⁺² in parotic acini and duct cells of rats. It thus acts as therapeutic agent for xerostomia.

특징 및 장점

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Daiichi-Sankyo. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301
• 예방조치 성명서: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable