SML0011

VAHA

≥98% (HPLC)

• 동의어(들): VAHA, Valproyl hydroxamic acid, VPA-HA
• 실험식(Hill 표기법): C₈H₁₇NO₂
• CAS Number: 106132-78-9
• Molecular Weight: 159.23
• MDL number: MFCD12756348
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825087
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• solubility: DMSO: ≥25 mg/mL
• 저장 온도: 2-8°C
• SMILES string: CCCC(CCC)C(=O)NO
• InChI: 1S/C8H17NO2/c1-3-5-7(6-4-2)8(10)9-11/h7,11H,3-6H2,1-2H3,(H,9,10)
• InChI key: ROJGIRXXBBBMPL-UHFFFAOYSA-N

설명

애플리케이션

VAHA may be used in cell signaling studies.

생화학적/생리학적 작용

Hydroxamic acid derivatives of valproic acid exhibit anticonvulsant activity with no teratogenic activity in mouse neural tube defect model. It is effective in the treatment of bipolar disorders.

VAHA (Valproyl hydroxamic acid) is an HDAC inhibitor with less activity than valproic acid against Class I enzymes but much greater Class II activity

VAHA is an HDAC inhibitor

특징 및 장점

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안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable