SML0149

3-Ethoxy-5,6-dibromosalicylaldehyde

≥95% (HPLC)

• 동의어(들): 2,3-Dibromo-5-ethoxy-6-hydroxy-benzaldehyde, 5,6-Dibromo-o-bourbonal
• 실험식(Hill 표기법): C₉H₈Br₂O₃
• CAS Number: 20041-64-9
• Molecular Weight: 323.97
• MDL number: MFCD00297095
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825197
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥95% (HPLC)
• 양식: powder
• 저장 조건: desiccated
• 색상: yellow
• solubility: DMSO: ≥15 mg/mL
• 저장 온도: 2-8°C
• SMILES string: CCOc1cc(Br)c(Br)c(C=O)c1O
• InChI: 1S/C9H8Br2O3/c1-2-14-7-3-6(10)8(11)5(4-12)9(7)13/h3-4,13H,2H2,1H3
• InChI key: MZAISYPWQNBWED-UHFFFAOYSA-N

설명

애플리케이션

3-Ethoxy-5,6-dibromosalicylaldehyde was used to study modulation of autophagy, JNK activation and NF-κB-mediated inflammation.

생화학적/생리학적 작용

3-Ethoxy-5,6-dibromosalicylaldehyde is a non-competitive inhibitor of Inositol-requiring enzyme 1 (IRE1). It inhibits XBP-1 splicing induced pharmacologically in human cells. 3-Ethoxy-5,6-dibromosalicylaldehyde potently inhibits the endoribonuclease of IRE1 but does not inhibit RNases A, T1, or L.

3-Ethoxy-5,6-dibromosalicylaldehyde is a non-competitive inhibitor of Inositol-requiring enzyme 1 (IRE1); potent inhibitor of endoribonuclease of IRE1

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302,H317
• 예방조치 성명서: P280 - P301 + P312 + P330 - P302 + P352
• Hazard Classifications: Acute Tox. 4 Oral - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable