SML0173

Reversan

≥98% (HPLC)

• 동의어(들): CBLC4H10, N-[3-(4-Morpholinyl)propyl]-5,7-diphenyl-pyrazolo[1,5-a]pyrimidine-3-carboxamide
• 실험식(Hill 표기법): C₂₆H₂₇N₅O₂
• CAS Number: 313397-13-6
• Molecular Weight: 441.52
• MDL number: MFCD01528184
• UNSPSC 코드: 12161501
• PubChem Substance ID: 329825203
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: faintly yellow to yellow
• solubility: DMSO: ≥8 mg/mL at ~60 °C
• 저장 온도: 2-8°C
• SMILES string: O=C(NCCCN1CCOCC1)c2cnn3c(cc(nc23)-c4ccccc4)-c5ccccc5
• InChI: 1S/C26H27N5O2/c32-26(27-12-7-13-30-14-16-33-17-15-30)22-19-28-31-24(21-10-5-2-6-11-21)18-23(29-25(22)31)20-8-3-1-4-9-20/h1-6,8-11,18-19H,7,12-17H2,(H,27,32)
• InChI key: JTRXWCLQFAZHGP-UHFFFAOYSA-N

설명

애플리케이션

Reversan may be used in cell signaling studies.

생화학적/생리학적 작용

Nontoxic MRP1 function inhibitor; MRP1 and Pgp function inhibitor; multidrug transporter inhibitor

Reversan increases the efficacy of vincristine and etoposide and increases the sensitivity of murine models of neuroblastoma to conventional chemotherapy.

Reversan is a selective and nontoxic multidrug resistance-associated protein 1 (MRP1) and P-glycoprotein (P-gp) inhibitor.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable