SML0483

DpC

≥98% (HPLC)

• 동의어(들): Di-2-pyridylketone-4-cyclohexyl-4-methyl-3-thiosemicarbazone
• 실험식(Hill 표기법): C₁₉H₂₃N₅S
• CAS Number: 1382469-39-7
• Molecular Weight: 353.48
• MDL number: MFCD22666593
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825434
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 저장 조건: protect from light
• 색상: white to beige
• solubility: DMSO: 5 mg/mL (clear solution)
• 저장 온도: −20°C
• SMILES string: CN(C1CCCCC1)C(=S)N\N=C(\c2ccccn2)c3ccccn3
• InChI: 1S/C19H23N5S/c1-24(15-9-3-2-4-10-15)19(25)23-22-18(16-11-5-7-13-20-16)17-12-6-8-14-21-17/h5-8,11-15H,2-4,9-10H2,1H3,(H,23,25)
• InChI key: GNLZNQJBZNOUBM-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

DpC is an iron-chelating agent.

DpC is an iron-chelating agent. In four separate human pancreatic tumor cell lines, DpC significantly increased the expression and phosphorylation of the growth and metastasis suppressor, N-myc down-stream regulated gene 1 (NDRG1) and the cdk inhibitpr p21^CIP1/WAF. DpC completely blocked PANC-1 tumor growth in mouse xenografts.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301
• 예방조치 성명서: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable