추천 제품
Quality Level
분석
≥98% (HPLC)
양식
powder
색상
, faint yellow to dark orange
solubility
DMSO: 5 mg/mL, clear (warmed)
저장 온도
2-8°C
SMILES string
N2(NC(=O)C(=Cc3cc(ccc3)OCc4cc(ccc4)C)C2=O)c1ccccc1
InChI
1S/C24H20N2O3/c1-17-7-5-9-19(13-17)16-29-21-12-6-8-18(14-21)15-22-23(27)25-26(24(22)28)20-10-3-2-4-11-20/h2-15H,16H2,1H3,(H,25,27)
InChI key
ITMLWGWTDWJSRZ-UHFFFAOYSA-N
생화학적/생리학적 작용
Y16 blocks the binding of LARG, a DBL-family Rho guanine nucleotide exchange factor, with Rho (Kd = 80 nM). Y16 specifically inhibits LARG catalyzed activation of RhoA and RhoA signaling pathways. Y16 blocks the growth and migration of MCF7 breast cancer cells.
Y16 blocks the binding of LARG, a DBL-family Rho guanine nucleotide exchange factor.
특징 및 장점
This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the GTP Binding Proteins (Low Molecular Weight) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
기타 정보
Product is a racemic mixture of E/Z isomers.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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