SML1070

SR-58611A

≥98% (HPLC)

• 동의어(들): Amibegron, [[(7S)-7-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]-5,6,7,8-tetrahydro-2-naphthalenyl]oxy acetic acid ethyl ester hydrochloride
• 실험식(Hill 표기법): C₂₂H₂₆ClNO₄ · HCl
• CAS Number: 121524-09-2
• Molecular Weight: 440.36
• MDL number: MFCD00886563
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825649
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 광학 활성: [α]/D -75 to -95°, c = 0.5 in methanol
• 색상: white to beige
• solubility: DMSO: 20 mg/mL, clear
• 저장 온도: −20°C
• SMILES string: ClC1=CC([C@@H](O)CN[C@@H]2CC(C=C(OCC(OCC)=O)C=C3)=C3CC2)=CC=C1.Cl
• InChI: 1S/C22H26ClNO4.ClH/c1-2-27-22(26)14-28-20-9-7-15-6-8-19(11-17(15)12-20)24-13-21(25)16-4-3-5-18(23)10-16;/h3-5,7,9-10,12,19,21,24-25H,2,6,8,11,13-14H2,1H3;1H/t19-,21-;/m0./s1
• InChI key: NQIZCDQCNYCVAS-RQBPZYBGSA-N
• 유전자 정보: human ... ADRB3(155)

설명

생화학적/생리학적 작용

SR58611A is a potent, specific 3β adrenergic receptor agonist.

SR58611A is a potent, specific b3 adrenergic receptor agonist. The EC₅₀ for reduction of β3-mediated spontaneous motility in rat distal colon sections is 3.5 nM. Minimal anti-depressant efficacious doses for SR58611A are 0.1-0.3 mpk in rodent models.

특징 및 장점

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안전성 정보

• 픽토그램: GHS09
• 신호어: Warning
• 유해 및 위험 성명서: H410
• 예방조치 성명서: P273 - P391 - P501
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable