추천 제품
Quality Level
분석
≥98% (HPLC)
양식
powder
색상
, white to very dark brown
solubility
DMSO: 20 mg/mL, clear
저장 온도
2-8°C
SMILES string
OCCNC1CCCC2=C1NC3=C2C=C(C4=CC=CC=C4)C=C3
InChI
1S/C20H22N2O/c23-12-11-21-19-8-4-7-16-17-13-15(14-5-2-1-3-6-14)9-10-18(17)22-20(16)19/h1-3,5-6,9-10,13,19,21-23H,4,7-8,11-12H2
InChI key
RXIUMAOXORBRCY-UHFFFAOYSA-N
관련 카테고리
애플리케이션
CASIN has been used as a cell division control protein 42 homolog (Cdc42) inhibitor:
- to study its effects on the stimulation of extracellular vesicles (EVs) in intestinal epithelial cells
- to study its effects on mice jejunum
- to study its effects on microbial adhesion-triggered endocytosis (MATE) vesicle morphology in segmented filamentous bacteria (SFB)-colonized mice
생화학적/생리학적 작용
CASIN is an inhibitor of Cdc42 GTPase, a small GTPase of the Rho-subfamily that plays important roles in cytoskeleton organization, cell cycle progression, signal transduction, and vesicle trafficking. CASIN generated a rejuvenated phenotype of Hematopoietic stem cells (HSCs), reversing the aging-related and polarity phenotype of aged HSCs to that of young HSCs in vivo..
CASIN is an inhibitor of Cdc42 GTPase.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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