SML1285

Febuxostat

98.5-102.0% (dry basis), powder, xanthine oxidase inhibitor

• 동의어(들): 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid, Adenuric, Atenuri, Uloric
• 실험식(Hill 표기법): C₁₆H₁₆N₂O₃S
• CAS Number: 144060-53-7
• Molecular Weight: 316.37
• MDL number: MFCD00871598
• UNSPSC 코드: 51111800
• PubChem Substance ID: 329825764
• NACRES: NA.77

속성

• 제품명: Febuxostat, 98.5-102.0%
• Quality Level: 200
• 분석: 98.5-102.0%
• 양식: powder
• 저장 온도: 2-8°C
• SMILES string: CC(C)COC1=C(C#N)C=C(C2=NC(C)=C(C(O)=O)S2)C=C1
• InChI: 1S/C16H16N2O3S/c1-9(2)8-21-13-5-4-11(6-12(13)7-17)15-18-10(3)14(22-15)16(19)20/h4-6,9H,8H2,1-3H3,(H,19,20)
• InChI key: BQSJTQLCZDPROO-UHFFFAOYSA-N

설명

일반 설명

Febuxostat is a potent, non-purine compound, which inhibits the expression of cytokines/chemokines. It has also been reported to inhibit LPS-induced TNF-α, VCAM-1, MMP9 and MCP-1 expression.

생화학적/생리학적 작용

Febuxostat is a potent non-purine xanithine oxidase inhibitor.

Febuxostat is a potent non-purine xanithine oxidase inhibitor. Febuxostat is used in urate lowering therapies (ULTs) for the treatment of gout.

주의사항

Freely soluble in N,N-dimethyl formamide, Soluble in dimethyl sulfoxide, sparingly soluble in ethanol or trichloromethane, slightly soluble in methanol, practically insoluble in water

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable