SML1635

Brassinin

≥98% (HPLC)

• 동의어(들): Brassinine, Methyl N-(1H-indol-3-ylmethyl)-carbamodithioate, N-(1H-indol-3-ylmethyl)-carbamodithioic acid methyl ester
• 실험식(Hill 표기법): C₁₁H₁₂N₂S₂
• CAS Number: 105748-59-2
• Molecular Weight: 236.36
• MDL number: MFCD01632490
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825977
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 20 mg/mL, clear
• 저장 온도: −20°C
• SMILES string: S=C(SC)NCC1=CNC2=C1C=CC=C2
• InChI: 1S/C11H12N2S2/c1-15-11(14)13-7-8-6-12-10-5-3-2-4-9(8)10/h2-6,12H,7H2,1H3,(H,13,14)
• InChI key: QYKQWFZDEDFELK-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

Brassinin is a phytoalexin isolated from cruciferous vegetables that exhibits anticancer, chemopreventive, antiproliferative and antifungal activities.

Brassinin is a phytoalexin isolated from cruciferous vegetables that exhibits anticancer, chemopreventive, antiproliferative and antifungal activities. In lung cancer cells, brassinin inhibits constitutive and IL-6-inducible STAT3 signaling through modulation of PIAS-3 and SOCS-3. It appears that brassinin induces apoptosis in PC-3 prostate cancer cells via the suppression of PI3K/Akt/mTOR/S6K1 signaling.

기타 정보

air sensitive

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3