SML1707

Temoporfin

≥90% (HPLC)

• 동의어(들): 3,3′,3′′,3′′′-(7,8-Dihydro-21H,23H-porphine-5,10,15,20-tetrayl)tetrakis-phenol, 5,10,15,20-Tetra(m-hydroxyphenyl)chlorin
• 실험식(Hill 표기법): C₄₄H₃₂N₄O₄
• CAS Number: 122341-38-2
• Molecular Weight: 680.75
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥90% (HPLC)
• 양식: powder
• 색상: dark brown to black
• solubility: DMSO: 2 mg/mL, clear (warmed)
• 저장 온도: −20°C
• InChI: 1S/C44H32N4O4/c49-29-9-1-5-25(21-29)41-33-13-15-35(45-33)42(26-6-2-10-30(50)22-26)37-17-19-39(47-37)44(28-8-4-12-32(52)24-28)40-20-18-38(48-40)43(36-16-14-34(41)46-36)27-7-3-11-31(51)23-27/h1-17,19,21-24,46-47,49-52H,18,20H2
• InChI key: LYPFDBRUNKHDGX-UHFFFAOYSA-N

설명

일반 설명

Temoporfin/(tetra[m-hydroxyphenyl]chlorin, m-THPC), is a hydrophobic second-generation photosensitizer. It is used in the palliative treatment of patients with advanced head and neck cancer by photodynamic therapy.

생화학적/생리학적 작용

Temoporfin is a photosensitizer for the photodynamic therapy.

Temoporfin is a photosensitizer for the photodynamic therapy. Temoporfin has been used clinically to treat advanced head and neck squamous cell carcinoma, and is being investigated for use in several other cancers.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable