SML1770

PhiKan083 hydrochloride

≥98% (HPLC)

• 동의어(들): 9-Ethyl-N-methyl-9H-Carbazole-3-methanamine hydrochloride, PK-083 hydrochloride, PK083 hydrochloride, PhiKan-083 hydrochloride
• 실험식(Hill 표기법): C₁₆H₁₈N₂ · HCl
• CAS Number: 1050480-30-2
• Molecular Weight: 274.79
• MDL number: MFCD07168924
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 저장 조건: desiccated
• 색상: white to beige
• solubility: H₂O: 2 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: CNCC1=CC2=C(C=C1)N(CC)C3=C2C=CC=C3.[H]Cl
• InChI key: IXWVUPURFWFRNE-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

Mutant p53 stabilizer

PhiKan083 is a small molecule that binds within a cavity on the surface of Y220C-mutated p53. This mutation, which is not involved in DNA interaction, causes a destabilization of the protein. PhiKan083 binding acts to stabilize the mutant p53 and slow the rate of denaturation.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319
• 예방조치 성명서: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable