추천 제품
Quality Level
분석
≥98% (HPLC)
양식
powder
색상
, yellow to light brown
solubility
DMSO: 10 mg/mL, clear
저장 온도
2-8°C
SMILES string
S=C(N\N=C2\c3c(c(cc(c3)Cl)Cl)NC\2=O)Nc1ccc(cc1)OC
InChI
1S/C16H12Cl2N4O2S/c1-24-10-4-2-9(3-5-10)19-16(25)22-21-14-11-6-8(17)7-12(18)13(11)20-15(14)23/h2-7H,1H3,(H2,19,22,25)(H,20,21,23)
InChI key
HPXWWBMVIMFLLU-UHFFFAOYSA-N
생화학적/생리학적 작용
NSC73306, a thiosemicarbazone, is a cell penetrant, cytotoxic agent that exhibits greater toxicity against cells expressing functional P-gp (P-glycoprotein) than against other cells.
NSC73306, a thiosemicarbazone, is a cell penetrant, cytotoxic agent that exhibits greater toxicity against cells expressing functional P-gp (P-glycoprotein) than against other cells. Irrespective of variations in cell line background, NSC73306 consistently demonstrated a Pgp-potentiated MDR-selective toxicity. It appears that NSC73306 is transported into the cell by copper transporter 1 (CTR1, SLC31A1). It is not P-gp inhibitor.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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