SML2141

Solifenacin succinate

≥98% (HPLC)

• 동의어(들): (1S)-(3R)-1-azabicyclo[2.2.2]oct-3-yl 3,4­dihydro-1-phenyl-2(1H)-iso-quinolinecarboxylate succinate, YM905
• 실험식(Hill 표기법): C₂₃H₂₆N₂O₂ · C₄H₆O₄
• CAS Number: 242478-38-2
• Molecular Weight: 480.55
• MDL number: MFCD00954234
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 광학 활성: [α]/D +35 to +45°, c = 1 in H₂O
• 저장 조건: desiccated
• 색상: white to beige
• solubility: H₂O: 2 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: OC(CCC(O)=O)=O.O=C(O[C@H]1CN2CCC1CC2)N3[C@@H](C4=CC=CC=C4)C5=CC=CC=C5CC3
• InChI: 1S/C23H26N2O2.C4H6O4/c26-23(27-21-16-24-13-10-18(21)11-14-24)25-15-12-17-6-4-5-9-20(17)22(25)19-7-2-1-3-8-19;5-3(6)1-2-4(7)8/h1-9,18,21-22H,10-16H2;1-2H2,(H,5,6)(H,7,8)/t21?,22-;/m0./s1
• InChI key: RXZMMZZRUPYENV-DZSUWJOWSA-N

설명

생화학적/생리학적 작용

Solifenacin succinate (SOL) blocks the cholinergic signals to M3 receptors by inhibiting the muscarinic M3 receptors in the bladder. This action prevents the contractions of the detrusor muscles in the urinary bladder wall, leading to relaxing the bladder as well as decreasing urinary urgency and nocturia. Thus, SOL is a widely used antimuscarinic agent for treating the contraction of the overactive bladder.

안전성 정보

• 픽토그램: GHS08
• 신호어: Warning
• 유해 및 위험 성명서: H361d
• 예방조치 성명서: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable