SML2174

MS012

≥98% (HPLC)

• 동의어(들): N2-Hexyl-6,7-dimethoxy-N4-(1-methylpiperidin-4-yl)quinazoline-2,4-diamine
• 실험식(Hill 표기법): C₂₂H₃₅N₅O₂
• CAS Number: 2089617-83-2
• Molecular Weight: 401.55
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear (warmed)
• 저장 온도: 2-8°C
• SMILES string: CN(CC1)CCC1NC2=C3C(C=C(OC)C(OC)=C3)=NC(NCCCCCC)=N2
• InChI: 1S/C22H35N5O2/c1-5-6-7-8-11-23-22-25-18-15-20(29-4)19(28-3)14-17(18)21(26-22)24-16-9-12-27(2)13-10-16/h14-16H,5-13H2,1-4H3,(H2,23,24,25,26)
• InChI key: ZYNUWSFRZCRKSN-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

G9a-like Protein (GLP) lysine methyl transferase Inhibitor

MS012 is a selective G9a-like Protein (GLP) lysine methyl transferase (PKMT) inhibitor with an IC50 value of 7 nM and over 140-fold selectivity for GLP over G9a and other methyl transferases tested.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable