SML2310

Thiodigalactoside

≥98% (HPLC)

• 동의어(들): Thiodigalactoside, β-D-Galactopyranosyl 1-thio-β-D-galactopyranoside, D-Galactopyranosylthio-β-D-galactopyranoside, TDG, D-Galactopyranosyl-β-D-thiogalactopyranoside
• 실험식(Hill 표기법): C₁₂H₂₂O₁₀S
• CAS Number: 51555-87-4
• Molecular Weight: 358.36
• MDL number: MFCD00057491
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: H₂O: 2 mg/mL, clear
• 저장 온도: −20°C
• SMILES string: S([C@@H]2O[C@@H]([C@@H]([C@@H]([C@H]2O)O)O)CO)C1O[C@@H]([C@@H]([C@@H]([C@H]1O)O)O)CO
• InChI: 1S/C12H22O10S/c13-1-3-5(15)7(17)9(19)11(21-3)23-12-10(20)8(18)6(16)4(2-14)22-12/h3-20H,1-2H2/t3-,4-,5+,6+,7+,8+,9-,10-,11+,12?/m1/s1
• InChI key: SYKYBMOFPMXDRQ-VVLLKYQZSA-N

설명

생화학적/생리학적 작용

Thiodigalactoside (TDG)is a potent inhibitor of galectin-1 (GAL1) that suppress tumor growth by inhibiting multiple cancer enhancing activities of galectin-1, including immune cell dysregulation, angiogenesis and protection against oxidative stress. Thiodigalactoside reverses galectin-1-induced cisplatin resistance in HCC cells. Thiodigalactoside significantly reduces body weight gain in diet-induced obese rats.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable