SML2341

Nω-Propyl-L-Arginine hydrochloride

≥98% (HPLC)

• 동의어(들): L-NPA, N(ω)-Propyl-L-arginine, N(w)-Propyl-L-arginine, N-ω-Propyl-L-arginine, N-Omega-propyl-L-Arginine, N5-[Imino(propylamino)methyl]-L-ornithine, NG-Propyl-L-arginine, NPA, NPLA, Nomega-Propyl-L-Arginine, PLA, p-ARG
• 실험식(Hill 표기법): C₉H₂₀N₄O₂ · xHCl
• CAS Number: 137361-05-8
• Molecular Weight: 216.28 (free base basis)
• MDL number: MFCD01320455
• UNSPSC 코드: 12352209

속성

• 분석: ≥98% (HPLC)
• 양식: film
• 저장 조건: desiccated
• 색상: colorless
• solubility: H₂O: 2 mg/mL, clear
• 저장 온도: −20°C
• SMILES string: CCCNC(NCCC[C@H](N)C(O)=O)=N
• InChI: 1S/C9H20N4O2/c1-2-5-12-9(11)13-6-3-4-7(10)8(14)15/h7H,2-6,10H2,1H3,(H,14,15)(H3,11,12,13)/t7-/m0/s1
• InChI key: AOMXURITGZJPKB-ZETCQYMHSA-N

설명

생화학적/생리학적 작용

Nω-Propyl-L-arginine (NPA; NPLA; p-ARG; L-PNA) is a substrate-competitive, reversible, potent and selective neuronal nitric oxide synthase (nNOS; bNOS) inhibitor (Ki = 57 nM/bovine nNOS, 8.5 μM/bovine eNOS, 180 μM/murine iNOS) widely used for probing nNOS-dependent physiological and pathological processes both in cultures and in animals in vivo.

Substrate-competitive, reversible, potent and selective neuronal nitric oxide synthase (nNOS; bNOS) inhibitor with in vitro and in vivo efficacy.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable