SML2397

Dooku1

≥98% (HPLC)

• 동의어(들): 2-((2,6-dichlorobenzyl)thio)-5-(1H-pyrrol-2-yl)-1,3,4-oxadiazole
• 실험식(Hill 표기법): C₁₃H₉Cl₂N₃OS
• CAS Number: 2253744-54-4
• Molecular Weight: 326.20
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: −20°C
• SMILES string: ClC(C=CC=C1Cl)=C1CSC2=NN=C(C3=CC=CN3)O2
• InChI: 1S/C13H9Cl2N3OS/c14-9-3-1-4-10(15)8(9)7-20-13-18-17-12(19-13)11-5-2-6-16-11/h1-6,16H,7H2
• InChI key: MNPOBXLPCWFONX-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

Dooku1, an analog of Yoda1, is a potent and selective antagonist of the mechanosensitive Piezo1 channel that inhibits endogenous Yoda1-activated channels. Dooku1 inhibits relaxation of relaxation of aorta caused by Yoda1.

potent and selective antagonist of the mechanosensitive Piezo1 channel that inhibits endogenous Yoda1-activated channels

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable