SML2803

Tebanicline hydrochloride

≥98% (HPLC)

• 동의어(들): (R)-5-(2-Azetidinylmethoxy)-2-chloropyridine hydrochloride, (R)-5-(Azetidin-2-ylmethoxy)-2-chloropyridine hydrochloride, 5-((2R)-Azetidin-2-ylmethoxy)-2-chloropyridine hydrochloride, ABT-594 hydrochloride, Ebanicline hydrochloride
• 실험식(Hill 표기법): C₉H₁₁ClN₂O · xHCl
• CAS Number: 198283-73-7
• Molecular Weight: 198.65 (free base basis)
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 저장 조건: desiccated
• 색상: white to beige
• solubility: H₂O: 2 mg/mL, clear
• 저장 온도: −20°C
• SMILES string: Clc1ncc(cc1)OC[C@@H]2NCC2
• InChI: 1S/C9H11ClN2O/c10-9-2-1-8(5-12-9)13-6-7-3-4-11-7/h1-2,5,7,11H,3-4,6H2/t7-/m1/s1
• InChI key: MKTAGSRKQIGEBH-SSDOTTSWSA-N

설명

생화학적/생리학적 작용

Partial agonist at neural nicotinic acetylcholine receptors, binding to both the α3β4 and the α4β2 subtypes

Tebanicline (ABT-594) is a partial agonist at neural nicotinic acetylcholine receptors, binding to both the α3β4 and the α4β2 subtypes. It is a less toxic analog of epibatidine with potent antinociceptive effects.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H336
• 예방조치 성명서: P261 - P271 - P304 + P340 + P312 - P403 + P233 - P405 - P501
• Hazard Classifications: STOT SE 3
• 표적 기관: Central nervous system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable