SML3027
FMF-04-159-2
≥98% (HPLC)
동의어(들):
(E)-N-(1-((3-(4-(dimethylamino)but-2-enamido)phenyl)sulfonyl)piperidin-4-yl)-4-(2,4,6-trichlorobenzamido)-1H-pyrazole-3-carboxamide
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C28H30Cl3N7O5S
CAS Number:
Molecular Weight:
683.01
MDL number:
UNSPSC 코드:
12352200
NACRES:
NA.77
추천 제품
Quality Level
분석
≥98% (HPLC)
양식
powder
색상
white to beige
solubility
DMSO: 2 mg/mL, clear
저장 온도
2-8°C
SMILES string
O=C(C1=NNC=C1NC(C2=C(Cl)C=C(Cl)C=C2Cl)=O)NC3CCN(S(=O)(C4=CC=CC(NC(/C=C/CN(C)C)=O)=C4)=O)CC3
InChI key
HZPYSAHDRSBARR-QPJJXVBHSA-N
생화학적/생리학적 작용
FMF-04-159-2 is a specific and potent covalent inhibitor Cyclin-dependent kinase 14 (CDK14) in cells that targets CDK14 at C218. FMF-04-159-2 reversibly inhibits CDK2, CDK10, and other TAIRE kinases (CDK15, CDK16, CDK17, and CDK18) with comparable potency to each other. It exhibits mild antiproliferative effects.
specific and potent covalent inhibitor CDK14 in cells that targets CDK14 at C218
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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