SML3164

CAM833

≥98% (HPLC)

• 동의어(들): CAM833A, N-(2-((2S,4R)-2-(((S)-1-(2-chloro-4-methoxyphenyl)ethyl)carbamoyl)-4-hydroxypyrrolidin-1-yl)-2-oxoethyl)-6-fluoroquinoline-2-carboxamide
• 실험식(Hill 표기법): C₂₆H₂₆ClFN₄O₅
• Molecular Weight: 528.96
• UNSPSC 코드: 12352107
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: FC1=CC=C(N=C(C(NCC(N2[C@H](C(N[C@H](C3=C(Cl)C=C(OC)C=C3)C)=O)C[C@@H](O)C2)=O)=O)C=C4)C4=C1
• InChI key: PMUWBFKMLGLUTF-KNUWZQJKSA-N

설명

생화학적/생리학적 작용

CAM833 is a potent and selective inhibitor of RAD51:BRCA2 interaction that inhibits RAD51 foci formation in A549 non-small cell lung carcinoma (NSCLC) cells. CAM833 suppresses extended RAD51 filament assembly. It potentiates the DNA damage by ionizing radiation in cells.

potent and selective inhibitor of RAD51:BRCA2 interaction

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable