SML3430
Benvitimod
≥98% (HPLC)
동의어(들):
(E)-2-Isopropyl-5-styrylbenzene-1,3-diol, 3,5-Dihydroxy-4-isopropyl-trans-stilbene, 3,5-Dihydroxy-4-isopropylstilbene, GSK-2894512, Tapinarof, WBI 1001
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About This Item
실험식(Hill 표기법):
C17H18O2
CAS Number:
Molecular Weight:
254.32
MDL number:
UNSPSC 코드:
41121706
NACRES:
NA.77
Quality Level
분석
≥98% (HPLC)
양식
powder
색상
, White to Very dark grey
solubility
DMSO: 2 mg/mL, clear
저장 온도
−20°C
SMILES string
CC(C1=C(C=C(C=C1O)/C=C/C2=CC=CC=C2)O)C
InChI
1S/C17H18O2/c1-12(2)17-15(18)10-14(11-16(17)19)9-8-13-6-4-3-5-7-13/h3-12,18-19H,1-2H3/b9-8+
InChI key
ZISJNXNHJRQYJO-CMDGGOBGSA-N
생화학적/생리학적 작용
Aryl hydrocarbon receptor (AHR) immunomodulator that inhibits skin inflammation and enhances skin barrier function.
Benvitimod (Tapinarof) is an aryl hydrocarbon receptor (AHR) immunomodulator that inhibits skin inflammation and enhances skin barrier function. Benvitimod is a metabolite, similar to resveratrol, produced by bacterial symbionts of entomopathogenic nematodes. It induces downregulation of inflammatory cytokines such as IL-17A, IL-17F, IL-19, IL-22, IL-23, and IL-1. Benvitimod also induces the expression of skin barrier genes related to keratinocyte differentiation.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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