SRP0294

FAP Active human

recombinant, expressed in baculovirus, ≥50% (SDS-PAGE)

• 동의어(들): FAPA, Fibroblast activation protein, α, Melanoma membrane-bound gelatinase 170 kDa, Seprase
• UNSPSC 코드: 12352204
• NACRES: NA.54

속성

• 재조합: expressed in baculovirus
• 분석: ≥50% (SDS-PAGE)
• 양식: aqueous solution
• 특이 활성도: ≥10.2 pmol/min-g
• 분자량: 85.5 kDa
• NCBI 수납 번호: NM_004460
• 배송 상태: dry ice
• 저장 온도: −70°C
• 유전자 정보: human ... FAP(2191)

설명

일반 설명

Human FAP (GenBank Accession No. NM_004460), (amino acids 29-end) with C-terminal HIS tag, MW = 85.5 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

애플리케이션

Active human FAP is useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Active human FAP has been used in a study to assess the role of FAP48 in HIV-associated lipodystrophy. Active human FAP has also been used in a study to investigate the current state of domino transplantation in surgical procedures and de novo amyloid neuropathy.

단위 정의

One unit is defined as the amount of enzyme that will cleave 1 pmol of substrate per min at 37°C

물리적 형태

Formulated in 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 200mM Imidazole, 3 mM DTT and 20% glycerol.

제조 메모

Thaw on ice. Upon first thaw, briefly spin tube containing enzyme to recover full content of the tube. Aliquot enzyme into single use aliquots. Store remaining undiluted enzyme in aliquots at -70°C. Note: Enzyme is very sensitive to freeze/thaw cycles.

안전성 정보

• 픽토그램: GHS08,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H315,H319,H360D
• 예방조치 성명서: P201 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
• Storage Class Code: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable