SRP2064

SRC1 (627-786), biotin,His tagged human

recombinant, expressed in E. coli, ≥80% (SDS-PAGE)

• 동의어(들): F-SRC-1, KAT13A, MGC129719, MGC129720, RIP160, SRC1, bHLHe42, bHLHe74
• UNSPSC 코드: 12352200
• NACRES: NA.26

속성

• 생물학적 소스: human
• 재조합: expressed in E. coli
• 분석: ≥80% (SDS-PAGE)
• 양식: frozen liquid
• 분자량: ~22 kDa
• 포장: pkg of 10 μg
• 저장 조건: avoid repeated freeze/thaw cycles
• 농도: 400 μg/mL
• 색상: clear colorless
• NCBI 수납 번호: NM_003743
• UniProt 수납 번호: Q15788
• 배송 상태: dry ice
• 저장 온도: −70°C
• 유전자 정보: human ... NCOA1(8648)

설명

생화학적/생리학적 작용

Steroid receptor coactivator 1 (SRC1) is a transcriptional coactivoator that mediates the activating functions of many of the nuclear hormone receptors. It is also known as NCoA1 and is a member of the SRC/p160 coactivator family. SRC1 has been shown to be over expressed in some cancers. SRC1 is a 160 kDa protein that contains several LXXLL motifs, which are involved in nuclear receptor interaction. The region 627-786 contains 3 LXXLL motifs that are involved in interaction with nuclear hormone receptorsand has been previously used in assays detecting ligand-dependent receptor-cofactor interactions. This protein does not contain any tag and will be useful for assays where a native untagged protein is desired.

물리적 형태

Clear and colorless frozen liquid solution

제조 메모

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable