SRP4633

VEGF-C human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

• 동의어(들): VEGFC, Vascular Endothelial Growth Factor-C
• MDL number: MFCD03458368
• UNSPSC 코드: 12352202
• NACRES: NA.32

속성

• 생물학적 소스: human
• 재조합: expressed in E. coli
• 분석: ≥90% (SDS-PAGE)
• 양식: lyophilized
• 분자량: 15-16 kDa
• 포장: pkg of 10 μg
• 저장 조건: avoid repeated freeze/thaw cycles
• 불순물: endotoxin, tested
• NCBI 수납 번호: Q6FH59
• 배송 상태: wet ice
• 저장 온도: −20°C
• 유전자 정보: human ... VEGFC(7424)

설명

일반 설명

The recombinant VEGF-C (vascular endothelial growth factor-C) is a 125 amino acid protein that lacks the N-terminal signal peptide (from T103 to R227 of Gene Bank U58111). Human VEGF-C exhibits about 85% homology with mouse VEGF-C. The VEGFC gene is mapped to human chromosome 4q34.3.

애플리케이션

VEGF-C human has been used to determine cell proliferation and survival.

생화학적/생리학적 작용

VEGF-C (vascular endothelial growth factor-C) promotes tumorigenesis, by inducing lymphatic metastasis. The production of VEGF-C is stimulated by pro-fibrotic transforming growth factor β. The main function of VEGF-C is to mediate lymphangiogenesis. Overexpression of VEGF-C in keratinocytes of skin causes dermal lymphatic vessel hyperplasia.

물리적 형태

Lyophilized without additives.

재구성

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in 0.1% acetic acid to a concentration of 0.1-1.0 mg/mL.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable