SRP6516

Albumin from human plasma

≥95% (SDS-PAGE)

• 동의어(들): Albumin protein, human Albumin, human Albumin protein, human plasma, human plasma Albumin proteinHSA, native Albumin, native Albumin protein
• EC Number: 232-692-7
• UNSPSC 코드: 12352202
• NACRES: NA.32

속성

• 생물학적 소스: human
• 분석: ≥95% (SDS-PAGE)
• 양식: lyophilized
• 분자량: 66 kDa
• 포장: pkg of 1G
• 색상: beige
• UniProt 수납 번호: P02768
• 배송 상태: wet ice
• 저장 온도: −20°C
• 유전자 정보: human ... ALB(213)

설명

일반 설명

Human albumin is encoded by ALB gene that is mapped to human chromosome 4q. The gene is developmentally regulated and is synthesized by the liver. The encoded protein has a molar mass of 65,000 Da and consists of a single polypeptide chain of 585 amino acids.

애플리케이션

Albumin has been used in ion exchange chromatography to compare the albumin isolated from whole human plasma. It has been used to bind to phage clones in phage binding assay.

생화학적/생리학적 작용

Human albumin is a globular unglycosylated serum protein that makes up for more than half of the total plasma or serum proteins. It functions in the maintenance of COP (cellular oncotic pressure). It binds to hydrophobic organic anions such as, bilirubin, long-chain fatty acids and haematin and some cations such as magnesium and calcium. It also serves as a secondary or tertiary carrier for steroids, vitamin D and thyroxine. It is involved in the catabolism of prostaglandins and metabolism of certain endogenous substances, such as lipids, and eicosanoids. It acts as a plasma buffer and scavenges oxygen free radicals, thus reducing the pathological effects of certain inflammatory diseases. Mutation in the gene coding for albumin leads to familial dysalbuminaemic hyperthyroidism.

물리적 형태

Lyophilized as a salt free solid.

안전성 정보

• 픽토그램: GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H334
• 예방조치 성명서: P261 - P284 - P304 + P340 + P312 - P501
• Hazard Classifications: Resp. Sens. 1A
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable