T0909

Tenoxicam

NSAID

• 동의어(들): 4-Hydroxy-2-methyl-N-2-pyridinyl-2H-thieno(2,3-e)-1,2-thiazine-3-carboxamide 1,1-dioxide
• 실험식(Hill 표기법): C₁₃H₁₁N₃O₄S₂
• CAS Number: 59804-37-4
• Molecular Weight: 337.37
• MDL number: MFCD00083502
• UNSPSC 코드: 12352202
• PubChem Substance ID: 24899922
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (perchloric acid titration)
• 양식: powder
• solubility: DMF: 25 mg/mL, clear, yellow-green
• SMILES string: O=C(NC1=NC=CC=C1)C2=C(O)C(SC=C3)=C3S(N2C)(=O)=O
• InChI: 1S/C13H11N3O4S2/c1-16-10(13(18)15-9-4-2-3-6-14-9)11(17)12-8(5-7-21-12)22(16,19)20/h2-7,17H,1H3,(H,14,15,18)
• InChI key: LZNWYQJJBLGYLT-UHFFFAOYSA-N

설명

애플리케이션

Tenoxicam has been used:

• as a non-steroidal anti-inflammatory agent (NSAID) to study its effects on root gravitropism in Arabidopsis thaliana
• as a standard in microanalysis of NSAIDs by spectrophotometry
• to test its effect on surface potential andmembrane fluidity modification in phosphoglyceride monolayers

생화학적/생리학적 작용

Non-steroidal antiinflammatory drug (NSAID) with comparatively low risk of renal or hepatic toxicity.

Tenoxicam (TX) possesses antipyretic and analgesic effects. It elicits radical scavenging activity and has the potential to treat enkylosing spondylitis, extra-articular diseases, acute gout, and rheumatic diseases. It is also effective in treating primary dysmenorrhea, postpartum uterine contraction pain, and post-operation backaches. TX is capable of inhibiting prostaglandin synthesis.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301 + H311 + H331
• 예방조치 성명서: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges