T1443

TCPOBOP

≥98% (HPLC), solid

• 동의어(들): 1,4-Bis-[2-(3,5-dichloropyridyloxy)]benzene, 3,3′,5,5′-Tetrachloro-1,4-bis(pyridyloxy)benzene
• 실험식(Hill 표기법): C₁₆H₈N₂O₂Cl₄
• CAS Number: 76150-91-9
• Molecular Weight: 402.06
• MDL number: MFCD00057368
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24278723
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: solid
• 색상: white
• solubility: DMSO: >10 mg/mL; H₂O: insoluble
• 저장 온도: 2-8°C
• SMILES string: Clc1cnc(Oc2ccc(Oc3ncc(Cl)cc3Cl)cc2)c(Cl)c1
• InChI: 1S/C16H8Cl4N2O2/c17-9-5-13(19)15(21-7-9)23-11-1-2-12(4-3-11)24-16-14(20)6-10(18)8-22-16/h1-8H
• InChI key: BAFKRPOFIYPKBQ-UHFFFAOYSA-N
• 유전자 정보: human ... NR1I3(9970)

설명

애플리케이션

TCPOBOP has been used for enhancing Mcl-1-Italics promoter functions in mouse hepatoma cells. TCPOBOP has also been used to study constitutive androstane receptor(CAR)-induced gene expression in mouse hepatocytes.

생화학적/생리학적 작용

TCPOBOP enhances the nuclear receptor CAR transactivation of cytochrome P450 (CYP), as dose-dependent direct agonist of CAR.

TCPOBOP enhances the nuclear receptor CAR transactivation of cytochrome P450 (CYP), as dose-dependent direct agonist of CAR. The most potent known member of the phenobarbital-like class of CYP-inducing agents.

특징 및 장점

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제조 메모

TCPOBOP is soluble in DMSO at a concentration that is greater than 10 mg/ml. It is insoluble in water.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)