T3452

Toloxatone

≥98% (HPLC), solid

• 동의어(들): 5-(Hydroxymethyl)-3-(3-methylphenyl)-2-oxazolidinone, Humoryl
• 실험식(Hill 표기법): C₁₁H₁₃NO₃
• CAS Number: 29218-27-7
• Molecular Weight: 207.23
• EC Number: 249-522-2
• MDL number: MFCD00865391
• UNSPSC 코드: 12161501
• PubChem Substance ID: 329826767
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: solid
• 저장 조건: desiccated
• solubility: DMSO: >10 mg/mL
• 저장 온도: 2-8°C
• SMILES string: Cc1cccc(c1)N2CC(CO)OC2=O
• InChI: 1S/C11H13NO3/c1-8-3-2-4-9(5-8)12-6-10(7-13)15-11(12)14/h2-5,10,13H,6-7H2,1H3
• InChI key: MXUNKHLAEDCYJL-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

Toloxatone is a reversible monoamine oxidase A inhibitor (MAOI) and antidepressant.

Toloxatone is a reversible monoamine oxidase A inhibitor (MAOI) and antidepressant. Toloxatone belongs to the aryloxazolidinones, a relatively new class of reversible monoamine oxidase A inhibitors (MAOI). Studies show that derivatives such as 3-aryloxazolidin-2-one (oxazolidinones), which are regularly used to treat gram positive infections, represent a new class of reversible as well as irreversible inhibitors for MAO-A and MAO-B enzymes that are able to inhibit protein synthesis and also used for neurodegenerative-type pathologies.

제조 메모

Toloxatone is soluble in DMSO at a concentration that is greater than 10 mg/ml.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves