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Merck
모든 사진(1)

주요 문서

T4382

Sigma-Aldrich

apo-Transferrin human

powder, ≥98% (agarose gel electrophoresis)

동의어(들):

Human transferrin, Siderophilin

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC 코드:
12352202
NACRES:
NA.75

생물학적 소스

human

Quality Level

분석

≥98% (agarose gel electrophoresis)

양식

powder

분자량

76-81 kDa

철 함량

≤0.005%

기술

cell culture | mammalian: suitable

불순물

HIV and HBsAg, source material tested negative

solubility

H2O: 50 mg/mL

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

유전자 정보

human ... TF(7018)

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일반 설명

Apo-transferrin human is a glycoprotein, possessing homologous carboxyl and amino domain. Both the domain binds to one molecule of iron. Only 30% of transferrin is saturated with iron in the amino domain. Apo-transferrin in human is encoded by the gene TF which is localized on human chromosome 3q22.1.

애플리케이션

Apo-Transferrin human has been used:
  • to determine the competitive binding of bismuth to albumin and transferrin by fast performance liquid chromatography (FPLC)
  • to study titanium-transferrin complex by electrochemical method
  • in the preparation of transferrin solution and in the formation of conjugates with ruthenium-complexes for cellular viability studies

생화학적/생리학적 작용

Apo-transferrin is an iron transport protein. The concentration of transferrin in blood plasma is about 35 μM. Transferrin also functions in the transport of therapeutic, diagnostic and toxic ions like Ga3+, Ru3+ and Al3+. Polymorphism in TF gene has pathological implications in Parkinson′s disease.
Apo-transferrin is required for the survival and differentiation of oligodendroglial cells.

기타 정보

Non-heme iron-transport protein.

결합

Similar to T 2252

면책조항

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


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