T5330

Tanshinone I

≥98% (HPLC)

• 동의어(들): Tanshinon I, Tanshinone A, Tanshinquinone I
• 실험식(Hill 표기법): C₁₈H₁₂O₃
• CAS Number: 568-73-0
• Molecular Weight: 276.29
• MDL number: MFCD00210563
• UNSPSC 코드: 12352205
• PubChem Substance ID: 329826820
• NACRES: NA.25

속성

• Quality Level: 200
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: red
• solubility: DMSO: 1 mg/mL
• 응용 분야: metabolomics; vitamins, nutraceuticals, and natural products
• 저장 온도: 2-8°C
• SMILES string: Cc1coc2-c3ccc4c(C)cccc4c3C(=O)C(=O)c12
• InChI: 1S/C18H12O3/c1-9-4-3-5-12-11(9)6-7-13-15(12)17(20)16(19)14-10(2)8-21-18(13)14/h3-8H,1-2H3
• InChI key: AIGAZQPHXLWMOJ-UHFFFAOYSA-N

설명

일반 설명

Tanshinone I (Tan I) is a phenolic compound primarily isolated from Danshen. It has an abietane diterpene norditerpenoid o-quinones structure. Tan I have poor water solubility.

애플리케이션

Tanshinone 1 has been used:

• to test its hematopoiesis effects on human leukemia cell lines and zebrafish xenograft models
• to study its anti-cancer effects on two breast cancer cell lines (MCF7 and MDA-MB-23)
• as a reference standard to quantify the bioactive component S. miltiorrhiza extract (SME) using high-performance liquid chromatography (HPLC)

생화학적/생리학적 작용

Phenanthrenequinone constituent of Chinese medicinal herb Danshen (Salvia miltiorrhiza). Modulates or prevents breast cancer metastasis by regulating adhesion molecules. Anti-inflammatory.

Phenanthrenequinone constituent of Chinese medicinal herb Danshen (Salvia miltiorrhiza). Modulates or prevents breast cancer metastasis by regulating adhesion molecules.Anti-inflammatory.

TanshinoneI is extensively studied for its anticancer properties, it was reported to inhibit cancer cell invasion, metastasis, and migration and is a potent antitumor agent. It also displays antibacterial, neuroprotective, memory-enhancing, and cardioprotective activities.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable