UC148

6-Hydroxychlorzoxazone

≥98% (HPLC), solid, chlorzoxazone metabolite

• 동의어(들): 5-Chloro-6-hydroxy-2(3H)-benzoxazolone, 5-Chloro-6-hydroxybenzoxazone
• 실험식(Hill 표기법): C₇H₄ClNO₃
• CAS Number: 1750-45-4
• Molecular Weight: 185.56
• MDL number: MFCD00143502
• UNSPSC 코드: 12161501
• PubChem Substance ID: 24724641
• NACRES: NA.77

속성

• Product Name: 6-Hydroxychlorzoxazone, ≥98% (HPLC)
• Quality Level: 200
• 분석: ≥98% (HPLC)
• 양식: solid
• 색상: white to pink
• solubility: methanol: soluble
• 저장 온도: 2-8°C
• SMILES string: Oc1cc2OC(=O)Nc2cc1Cl
• InChI: 1S/C7H4ClNO3/c8-3-1-4-6(2-5(3)10)12-7(11)9-4/h1-2,10H,(H,9,11)
• InChI key: AGLXDWOTVQZHIQ-UHFFFAOYSA-N

설명

애플리케이션

6-Hydroxychlorzoxazone has been used for HPLC-based metabolic assays of chlorzoxazone.

6-hydroxy Chlorzoxazone has been used: as a reference standard to monitor substrate depletion or 6-hydroxy chlorzoxazone formation by cytochrome P450 family 2 subfamily E member 1 (CYP2E1)in recombinant human enzyme screening. 6-Hydroxychlorzoxazone has been used for high-performance liquid chromatography (HPLC)-based metabolic assays of chlorzoxazone.

CYP2E1 & 1A2 metabolite of chlorzoxazone.

생화학적/생리학적 작용

6-hydroxy Chlorzoxazone is a novel metabolite of chlorzoxazone. It is formed by the hydroxylation of chlorzoxazone by cytochrome P450 family 2 subfamily E member 1 (CYP2E1) enzyme. The determination of formation and clearance of 6-hydroxychlorzoxazone is used as a reliable marker of CYP2E1 metabolic activity.

포장

Bottomless glass bottle. Contents are inside inserted fused cone.

제조 메모

6-Hydroxychlorzoxazone is soluble in methanol.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302,H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves