V8261

(±)-Vigabatrin

• 동의어(들): (R,S)-4-Amino-5-hexenoic acid, (±)-γ-Vinyl-GABA, (±)-4-Aminohexenoic acid
• 실험식(Hill 표기법): C₆H₁₁NO₂
• CAS Number: 68506-86-5
• Molecular Weight: 129.16
• EC Number: 270-929-6
• MDL number: MFCD00274577
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24278202
• NACRES: NA.77

속성

• Quality Level: 200
• 주관자: Lundbeck
• SMILES string: NC(CCC(O)=O)C=C
• InChI: 1S/C6H11NO2/c1-2-5(7)3-4-6(8)9/h2,5H,1,3-4,7H2,(H,8,9)
• InChI key: PJDFLNIOAUIZSL-UHFFFAOYSA-N
• 유전자 정보: human ... ABAT(18), GABBR1(2550), GABBR2(9568), GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562)

설명

생화학적/생리학적 작용

Irreversible GABA transaminase inhibitor. Increases intracellular concentration of GABA in nerve endings; possesses antiepileptic activity.

특징 및 장점

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the GABA Transporters, GABAA Receptors and Glutamate/GABA Synthesis and Metabolism pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Lundbeck. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H372
• 예방조치 성명서: P260 - P264 - P270 - P314 - P501
• Hazard Classifications: STOT RE 1
• 표적 기관: Eyes,Central nervous system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves