40334

N-Nitrosodiethylamine (NDEA) solution

certified reference material, 5000 μg/mL in methanol

• 동의어(들): Diethylnitrosamine
• CAS Number: 55-18-5
• MDL number: MFCD00013890
• UNSPSC 코드: 41116105

속성

• Grade: certified reference material
• Quality Level: 300
• 제품 라인: TraceCERT^®
• grade: TraceCERT^®
• CofA: current certificate can be downloaded
• 포장: ampule of 1 mL
• 농도: 5000 μg/mL in methanol
• 기술: HPLC: suitable; gas chromatography (GC): suitable
• 응용 분야: cleaning products; cosmetics; environmental; food and beverages; personal care
• 형식: single component solution
• 저장 온도: 2-8°C
• SMILES string: N(N=O)(CC)CC
• InChI: 1S/C4H10N2O/c1-3-6(4-2)5-7/h3-4H2,1-2H3
• InChI key: WBNQDOYYEUMPFS-UHFFFAOYSA-N

설명

일반 설명

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

N-Nitrosodiethylamine belongs to the group of toxic nitrosamines, known to show carcinogenic, mutagenic, and hepatotoxic properties. It is formed as a byproduct during food processing, pharmaceutical processing, and water treatment. As a result, they are generally found in water, fish, meat, drug substances, etc.

애플리케이션

The CRM can be used as follows:

• Simultaneous analysis of N-nitrosodiethanolamine, N-nitrosodiethylamine, triethanolamine, diethanolamine in cosmetic samples using liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS)
• Solid phase extraction of N-nitrosodimethylamine and N-nitrosomethylethylamine from eight sartans, ranitidine, and metformin and also the fortified products of these drugs, for quantification by gas chromatography-tandem mass spectrometry (GC-MS/MS)
• Multi-residue analysis of seven restricted nitrosamines in two body creams and two shower gel samples by vortex-assisted reversed-phase dispersive liquid-liquid microextraction (VA-RP-DLLME) and liquid chromatography-mass spectrometry (LC-MS)
• Quantitative analysis of four nitrosamines in four sartan drug substances— candesartan cilexetil, olmesartan medoxomi, irbesartan, and valsartan, by gas chromatography-tandem mass spectrometry (GC-MS/MS)
• Determination of eight volatile nitrosamines in 28 popular meat product samples using ultrasonic solvent extraction combined with solid phase microextraction (SPME) and GC-MS

기타 정보

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

법적 정보

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS02,GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H225,H301 + H311 + H331,H350,H370
• 예방조치 성명서: P202 - P210 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Flam. Liq. 2 - STOT SE 1
• 표적 기관: Eyes,Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3