PHL84241

Mogrol

phyproof^® Reference Substance

• 동의어(들): (3β,9β,10α,11α,24R)-9-Methyl-19-norlanost-5-ene-3,11,24,25-tetrol
• 실험식(Hill 표기법): C₃₀H₅₂O₄
• CAS Number: 88930-15-8
• Molecular Weight: 476.73
• MDL number: MFCD29904541
• UNSPSC 코드: 41116107
• NACRES: NA.24

속성

• Grade: primary reference standard
• 제품 라인: phyproof^® Reference Substance
• 분석: ≥90.0% (HPLC)
• 양식: solid
• 제조업체/상표: PhytoLab
• SMILES string: O[C@H]1[C@@]2([C@H]([C@]4([C@@]([C@H](CC4)[C@@H](CC[C@@H](O)C(O)(C)C)C)(C1)C)C)CC=C3[C@H]2CC[C@@H](C3(C)C)O)C
• InChI: 1S/C30H52O4/c1-18(9-13-24(32)27(4,5)34)19-15-16-28(6)22-12-10-20-21(11-14-23(31)26(20,2)3)30(22,8)25(33)17-29(19,28)7/h10,18-19,21-25,31-34H,9,11-17H2,1-8H3/t18-,19-,21-,22+,23+,24-,25-,28+,29-,30+/m1/s1
• InChI key: JLYBBRAAICDTIS-AYEHCKLZSA-N

설명

일반 설명

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. K

생화학적/생리학적 작용

Mogrol is an aglycone of mogrosides from Siraitia grosvenorii that exhibits neuroprotective and anticancer activities. It induces apoptosis in K562 leukemia cells through suppression of ERK1/2 and STAT3 pathways. Mogrol appears to ameliorate the memory impairment caused by Aβ1-42 in mice. Mogrol increases AMPK activity in hepatocytes and suppresses adipocyte differentiation in 3T3-L1 cells.

aglycone of mogrosides from Siraitia grosvenorii that exhibits neuroprotective and anticancer activities; suppresses adipocyte differentiation

법적 정보

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3