1357056

Leflunomide Related Compound B

United States Pharmacopeia (USP) Reference Standard

• 동의어(들): 2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide
• 실험식(Hill 표기법): C₁₂H₉F₃N₂O₂
• CAS Number: 108605-62-5
• Molecular Weight: 270.21
• MDL number: MFCD00910058
• UNSPSC 코드: 41116107
• PubChem Substance ID: 329750239
• NACRES: NA.24

속성

• Grade: pharmaceutical primary standard
• API family: leflunomide
• 제조업체/상표: USP
• 응용 분야: pharmaceutical (small molecule)
• 형식: neat
• SMILES string: O=C(/C(C#N)=C(O)/C)NC1=CC=C(C(F)(F)F)C=C1
• InChI: 1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,18H,1H3,(H,17,19)/b10-7-
• InChI key: UTNUDOFZCWSZMS-YFHOEESVSA-N
• 유전자 정보: human ... DHODH(1723)

설명

일반 설명

Leflunomide Related Compound B (2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide is a malononitrilamide which is a water soluble metabolite of Leflunomide. It is considered as a noncompetitive inhibitor of dihydro-orotate dehydrogensae. This metabolite has been reported to initially target activated lymphocytes.

분석 메모

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

기타 정보

Sales restrictions may apply.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable